 |
|
As a diagnostic to predict patient outcome
or response to therapy |
|
|
As a surrogate endpoint in a clinical trial
leading to smaller, shorter and successful clinical trials |
|
|
Confirmation of a drug's pharmacological
or biological mechanism of action |
|
|
As an aid for clinical trial protocol design |
|
|
Patient selection, dose selection and minimization
of safety risks |
|
|
Extraction of DNA and RNA from snap-frozen
tissue and blood |
|
|
As an aid to corporate decision making at
go/no-go milestones |
|
|
Data to justify accelerated provisional regulatory
approval of a drug |
